human PEX6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PEX6.
shAAV-218648
AAV-h-PEX6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PEX6 (peroxisomal biogenesis factor 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HMLR2; PAF-2; PAF2; PBD4A; PDB4B; PXAAA1
Description (Vector)
PEX6 encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6.
Gene ID
5190
Gene Name (Vector)
peroxisomal biogenesis factor 6
Gene Symbol
PEX6
HGNC ID
HGNC:8859
ORF Size (aa)
2943
ORF Size (bp)
2943 bp
RefSeq ID
NM_000287
RefSeq Synonyms
NM_001316313, NM_000287, BC048331,
Species
human
UniGene ID
Hs.656425
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.