human PER1 shRNA silencing AAV

Name
AAV-h-PER1-shRNA

Cat No
shAAV-218621

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PER1.

shAAV-218621

AAV-h-PER1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PER1 (period circadian clock 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hPER; PER; RIGUI

Description (Vector)

PER1 is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. Alternative splicing has been observed in this gene; however, these variants have not been fully described.

Gene ID

5187

Gene Name (Vector)

period circadian clock 1

Gene Symbol

PER1

HGNC ID

HGNC:8845

ORF Size (aa)

3873

ORF Size (bp)

3873 bp

RefSeq ID

NM_002616

RefSeq Synonyms

NM_002616, BC137346, BC072458, BC028207,

Species

human

UniGene ID

Hs.445534

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.