human PDPN shRNA silencing AAV

Name
AAV-h-PDPN-shRNA

Cat No
shAAV-218551

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PDPN.

shAAV-218551

AAV-h-PDPN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PDPN (podoplanin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

AGGRUS; GP36; Gp38; GP40; HT1A-1; OTS8; PA2.26; T1A; T1A-2; T1A2; TI1A

Description (Vector)

PDPN encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene ID

10630

Gene Name (Vector)

podoplanin

Gene Symbol

PDPN

HGNC ID

HGNC:29602

ORF Size (aa)

717

RefSeq ID

NM_006474

RefSeq Synonyms

NM_198389, NM_006474, NM_001006625, NM_001006624, BC022812, BC014668,

Species

human

UniGene ID

Hs.468675

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.