human PDK1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PDK1.
shAAV-218534
AAV-h-PDK1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PDK1 (pyruvate dehydrogenase kinase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.
Gene ID
5163
Gene Name (Vector)
pyruvate dehydrogenase kinase 1
Gene Symbol
PDK1
HGNC ID
HGNC:8809
ORF Size (aa)
1311
ORF Size (bp)
1311 bp
RefSeq ID
NM_002610
RefSeq Synonyms
NM_002610, NM_001278549, BC039158,
Species
human
UniGene ID
Hs.470633
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.