human MTFR1 shRNA silencing AAV

Name 
AAV-h-MTFR1-shRNA
Cat No 
shAAV-218491
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MTFR1.

shAAV-218491
AAV-h-MTFR1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MTFR1 (mitochondrial fission regulator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
chondrocyte protein with a poly-proline region; CHPPR; FAM54A2; mitochondrial fission regulator 1
Description (eCommerce)
May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15390].
Description (Vector)
MTFR1 encodes a mitochondrial protein that is characterized by a poly-proline rich region. A chicken homolog of this protein promotes mitochondrial fission and the mouse homolog protects cells from oxidative stress. A related pseudogene of this gene is found on chromosome X.
Gene ID
9650
Gene Name (eCommerce)
mitochondrial fission regulator 1
Gene Name (Vector)
mitochondrial fission regulator 1
Gene Symbol
MTFR1
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1002
ORF Size (bp)
1002 bp
Protein Name (eCommerce)
Mitochondrial fission regulator 1
RefSeq ID
NM_014637
RefSeq Synonyms
NM_014637, NM_001145839, NM_001145838, BC043498, BC036116,
Research Areas
Mitochondrion
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
May play a role in mitochondrial aerobic respiration. May also regulate mitochondrial organization and fission (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15390].
UniGene ID
Hs.584788
UniProt ID (eCommerce)
Q15390

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.