human PDE1C shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PDE1C.
shAAV-218463
AAV-h-PDE1C-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PDE1C (phosphodiesterase 1C). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
cam-PDE 1C; hCam-3; Hcam3
Description (Vector)
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 (PubMed 1326532)).(supplied by OMIM, Oct 2009)
Gene ID
5137
Gene Name (Vector)
phosphodiesterase 1C
Gene Symbol
PDE1C
HGNC ID
HGNC:8776
ORF Size (aa)
1905
ORF Size (bp)
1905 bp
RefSeq ID
NM_005020
RefSeq Synonyms
NM_005020, NM_001322059, NM_001322058, NM_001322057, NM_001322056, NM_001322055, NM_001191059, NM_001191058, NM_001191057, NM_001191056, BC022525, BC022479,
Species
human
UniGene ID
Hs.655694
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.