human PDCD6 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PDCD6.
shAAV-218446
AAV-h-PDCD6-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PDCD6 (programmed cell death 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ALG-2; ALG2; PEF1B
Description (Vector)
PDCD6 encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. PDCD6 product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5.
Gene ID
10016
Gene Name (Vector)
programmed cell death 6
Gene Symbol
PDCD6
HGNC ID
HGNC:8765
ORF Size (aa)
570
RefSeq ID
NM_013232
RefSeq Synonyms
NM_013232, NM_001267559, NM_001267558, NM_001267557, NM_001267556, BC110291, BC106706, BC012384,
Species
human
UniGene ID
Hs.50823
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.