human PDAP1 shRNA silencing AAV

Name 
AAV-h-PDAP1-shRNA
Cat No 
shAAV-218428
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PDAP1.

shAAV-218428
AAV-h-PDAP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PDAP1 (PDGFA associated protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
28 kDa heat- and acid-stable phosphoprotein; HASPP28; PAP; PAP1; PDGFA-associated protein 1; PDGF-associated protein
Description (eCommerce)
PDGFA-associated protein 1 (PDAP1) is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. PDGFA in rodents has been shown to bind PDGFA with a low affinity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13442].
Description (Vector)
PDAP1 is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity.
Gene ID
11333
Gene Name (eCommerce)
PDGFA associated protein 1
Gene Name (Vector)
PDGFA associated protein 1
Gene Symbol
PDAP1
HGNC ID
HGNC:14634
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
546
Protein Name (eCommerce)
28 kDa heat- and acid-stable phosphoprotein
RefSeq ID
NM_014891
RefSeq Synonyms
NM_014891, BC007873, BC000684,
Research Areas
Signal Transduction
Research Areas (Faceted)
signal_transduction
Species
human
Target Sentence
PDGFA-associated protein 1 (PDAP1) is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. PDGFA in rodents has been shown to bind PDGFA with a low affinity [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q13442].
UniGene ID
Hs.632296
UniProt ID (eCommerce)
Q13442

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.