human PCOLCE shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PCOLCE.
shAAV-218399
AAV-h-PCOLCE-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PCOLCE (procollagen C-endopeptidase enhancer). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PCPE; PCPE-1; PCPE1
Description (Vector)
Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity.
Gene ID
5118
Gene Name (Vector)
procollagen C-endopeptidase enhancer
Gene Symbol
PCOLCE
HGNC ID
HGNC:8738
ORF Size (aa)
1350
ORF Size (bp)
1350 bp
RefSeq ID
NM_002593
RefSeq Synonyms
NM_002593, BC033205, BC000574,
Species
human
UniGene ID
Hs.202097
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.