human PCK2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human PCK2.
shAAV-218383
AAV-h-PCK2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human PCK2 (phosphoenolpyruvate carboxykinase 2, mitochondrial). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PEPCK; PEPCK-M; PEPCK2
Description (Vector)
PCK2 encodes a member of the phosphoenolpyruvate carboxykinase (GTP) family. The protein is a mitochondrial enzyme that catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the presence of GTP. A cytosolic form encoded by a different gene has also been characterized and is the key enzyme of gluconeogenesis in the liver. The encoded protein may serve a similar function, although it is constitutively expressed and not modulated by hormones such as glucagon and insulin that regulate the cytosolic form. Alternatively spliced transcript variants have been described.
Gene ID
5106
Gene Name (Vector)
phosphoenolpyruvate carboxykinase 2, mitochondrial
Gene Symbol
PCK2
HGNC ID
HGNC:8725
ORF Size (aa)
1923
ORF Size (bp)
1923 bp
RefSeq ID
NM_004563
RefSeq Synonyms
NM_004563, NM_001308054, NM_001291556, NM_001018073, BC001454,
Species
human
UniGene ID
Hs.75812
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.