human PCK1 shRNA silencing AAV

Name 
AAV-h-PCK1-shRNA
Cat No 
shAAV-218382
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human PCK1.

shAAV-218382
AAV-h-PCK1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PCK1 (phosphoenolpyruvate carboxykinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PEPCK-C; PEPCK1; PEPCKC
Description (Vector)
PCK1 is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Gene ID
5105
Gene Name (Vector)
phosphoenolpyruvate carboxykinase 1
Gene Symbol
PCK1
HGNC ID
HGNC:8724
ORF Size (aa)
1869
ORF Size (bp)
1869 bp
RefSeq ID
NM_002591
RefSeq Synonyms
NM_002591, BC023978,
Species
human
UniGene ID
Hs.1872

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.