human PAX1 shRNA silencing AAV

Name
AAV-h-PAX1-shRNA

Cat No
shAAV-218268

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human PAX1.

shAAV-218268

AAV-h-PAX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PAX1 (paired box 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HUP48; OFC2

Description (Vector)

PAX1 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. PAX1 plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. PAX1 is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations.

Gene ID

5075

Gene Name (Vector)

paired box 1

Gene Symbol

PAX1

HGNC ID

HGNC:8615

ORF Size (aa)

1323

ORF Size (bp)

1323 bp

RefSeq ID

NM_006192

RefSeq Synonyms

NM_006192, NM_001257096, BC069134,

Species

human

UniGene ID

Hs.349082

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.