human PAK1 shRNA silencing AAV

Cat. No: shAAV-218151

Availability: 4-5 weeks

Name: AAV-h-PAK1-shRNA

This is an AAV expressing shRNA for silencing of Human PAK1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PAK1
Gene Name: p21 (RAC1) activated kinase 1
Gene ID: 5058
Gene Synonyms: PAKalpha
ORF Size: 1638 bp
RefSeq#: NM_002576
Gene Description: PAK1 encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.435714
HGNC ID: HGNC:8590