human PAFAH2 shRNA silencing AAV

Name
AAV-h-PAFAH2-shRNA

Cat No
shAAV-218132

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PAFAH2.

shAAV-218132

AAV-h-PAFAH2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PAFAH2 (platelet activating factor acetylhydrolase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HSD-PLA2

Description (Vector)

PAFAH2 encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.

Gene ID

5051

Gene Name (Vector)

platelet activating factor acetylhydrolase 2

Gene Symbol

PAFAH2

HGNC ID

HGNC:8579

ORF Size (aa)

1179

ORF Size (bp)

1179 bp

RefSeq ID

NM_000437

RefSeq Synonyms

NM_000437, BC001158,

Species

human

UniGene ID

Hs.477083

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.