human PAFAH2 shRNA silencing AAV

Cat. No: shAAV-218132

Availability: 4-5 weeks

Name: AAV-h-PAFAH2-shRNA

This is an AAV expressing shRNA for silencing of Human PAFAH2.

Request a Quote

Please enter your email address and we'll be in touch with more information:

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PAFAH2
Gene Name: platelet activating factor acetylhydrolase 2
Gene ID: 5051
Gene Synonyms: HSD-PLA2
ORF Size: 1179 bp
RefSeq#: NM_000437
Gene Description: PAFAH2 encodes platelet-activating factor acetylhydrolase isoform 2, a single-subunit intracellular enzyme that catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). However, this lipase exhibits a broader substrate specificity than simply platelet activating factor. Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist, and both are multi-subunit enzymes. Additionally, there is a single-subunit serum isoform of this enzyme.
UniGene ID: Hs.477083
HGNC ID: HGNC:8579