human P2RX6 shRNA silencing AAV

Name 
AAV-h-P2RX6-shRNA
Cat No 
shAAV-218049
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human P2RX6.

shAAV-218049
AAV-h-P2RX6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human P2RX6 (purinergic receptor P2X 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
P2RXL1; P2X6; P2XM
Description (Vector)
P2RX6 belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.
Gene ID
9127
Gene Name (Vector)
purinergic receptor P2X 6
Gene Symbol
P2RX6
HGNC ID
HGNC:8538
ORF Size (aa)
1296
ORF Size (bp)
1296 bp
RefSeq ID
NM_005446
RefSeq Synonyms
NM_005446, NM_001159554, BC109209, BC047287, BC033488,
Species
human
UniGene ID
Hs.113275

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.