human P2RX3 shRNA silencing AAV

Name
AAV-h-P2RX3-shRNA

Cat No
shAAV-218041

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human P2RX3.

shAAV-218041

AAV-h-P2RX3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human P2RX3 (purinergic receptor P2X 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

P2X3

Description (Vector)

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Gene ID

5024

Gene Name (Vector)

purinergic receptor P2X 3

Gene Symbol

P2RX3

HGNC ID

HGNC:8534

ORF Size (aa)

1191

RefSeq ID

NM_002559

RefSeq Synonyms

NM_002559, BC109287, BC074793, BC074792, BC069162,

Species

human

UniGene ID

Hs.146738

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.