human OTX1 shRNA silencing AAV

Name 
AAV-h-OTX1-shRNA
Cat No 
shAAV-218010
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human OTX1.

shAAV-218010
AAV-h-OTX1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OTX1 (orthodenticle homeobox 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
OTX1 encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternate splicing results in two transcript variants that encoded the same protein.
Gene ID
5013
Gene Name (Vector)
orthodenticle homeobox 1
Gene Symbol
OTX1
HGNC ID
HGNC:8521
ORF Size (aa)
1065
ORF Size (bp)
1065 bp
RefSeq ID
NM_014562
RefSeq Synonyms
NM_014562, NM_001199770, BC007621,
Species
human
UniGene ID
Hs.445340

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.