human OTOA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human OTOA.
shAAV-217983
AAV-h-OTOA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human OTOA (otoancorin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CT108; DFNB22
Description (Vector)
OTOA is specifically expressed in the inner ear, and is located at the interface between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22 (DFNB22). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
146183
Gene Name (Vector)
otoancorin
Gene Symbol
OTOA
HGNC ID
HGNC:16378
ORF Size (aa)
3420
ORF Size (bp)
3420 bp
RefSeq ID
NM_144672
RefSeq Synonyms
NM_170664, NM_144672, NM_001161683, BC129993,
Species
human
UniGene ID
Hs.408336
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.