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human OSBPL3 shRNA silencing AAV

Name 
AAV-h-OSBPL3-shRNA
Cat No 
shAAV-217951
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human OSBPL3.

shAAV-217951
AAV-h-OSBPL3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OSBPL3 (oxysterol binding protein like 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ORP3; ORP-3; OSBP3; OSBP-related protein 3; oxysterol-binding protein-related protein 3
Description (eCommerce)
Oxysterol-binding protein-related protein 3 (ORP3) is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. ORP3 is involved in the regulation of cell adhesion and organization of the actin cytoskeleton [taken from NCBI Entrez Gene (Gene ID: 26031)].
Description (Vector)
OSBPL3 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Several transcript variants encoding different isoforms have been identified.
Gene ID
26031
Gene Name (eCommerce)
oxysterol binding protein like 3
Gene Name (Vector)
oxysterol binding protein like 3
Gene Symbol
OSBPL3
HGNC ID
HGNC:16370
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2664
ORF Size (bp)
2664 bp
Protein Name (eCommerce)
Oxysterol-binding protein-related protein 3
RefSeq ID
NM_015550
RefSeq Synonyms
NM_145322, NM_145321, NM_145320, NM_015550, BC017731,
Research Areas
Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Oxysterol-binding protein-related protein 3 (ORP3) is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. ORP3 is involved in the regulation of cell adhesion and organization of the actin cytoskeleton [taken from NCBI Entrez Gene (Gene ID: 26031)].
UniGene ID
Hs.520259
UniProt ID (eCommerce)
Q9H4L5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.