human OSBPL2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human OSBPL2.
shAAV-217949
AAV-h-OSBPL2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human OSBPL2 (oxysterol binding protein like 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DFNA67; DNFA67; ORP-2; ORP2
Description (Vector)
OSBPL2 encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
Gene ID
9885
Gene Name (Vector)
oxysterol binding protein like 2
Gene Symbol
OSBPL2
HGNC ID
HGNC:15761
ORF Size (aa)
1443
ORF Size (bp)
1443 bp
RefSeq ID
NM_144498
RefSeq Synonyms
NM_144498, NM_014835, NM_001278649, BC004455, BC000296,
Species
human
UniGene ID
Hs.473254
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.