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human OPRL1 shRNA silencing AAV

Name 
AAV-h-OPRL1-shRNA
Cat No 
shAAV-217446
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human OPRL1.

shAAV-217446
AAV-h-OPRL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OPRL1 (opioid related nociceptin receptor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
KOR-3; NOCIR; NOP; NOPr; OOR; ORL1
Description (Vector)
OPRL1 is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities, particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene, regulator of G-protein signalling 19 (RGS19), located on the opposite strand. Three transcript variants encoding the same protein have been found for this gene.
Gene ID
4987
Gene Name (Vector)
opioid related nociceptin receptor 1
Gene Symbol
OPRL1
HGNC ID
HGNC:8155
ORF Size (aa)
1113
ORF Size (bp)
1113 bp
RefSeq ID
NM_000913
RefSeq Synonyms
NM_182647, NM_001318855, NM_001318854, NM_001318853, NM_001200019, NM_000913, BC038433,
Species
human
UniGene ID
Hs.2859

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.