human OPN1MW shRNA silencing AAV

Cat. No: shAAV-217433

Availability: 6-8 weeks

Name: AAV-h-OPN1MW-shRNA

This is an AAV expressing shRNA for silencing of Human OPN1MW.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: OPN1MW
Gene Name: opsin 1 (cone pigments), medium-wave-sensitive
Gene ID: 2652
Gene Synonyms: CBBM; CBD; COD5; GCP; GOP; OPN1MW1
ORF Size: 1095 bp
RefSeq#: NM_000513
Gene Description: OPN1MW encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness.
UniGene ID: Hs.247787
HGNC ID: HGNC:4206