human OPN1MW shRNA silencing AAV

Name
AAV-h-OPN1MW-shRNA

Cat No
shAAV-217433

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human OPN1MW.

shAAV-217433

AAV-h-OPN1MW-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human OPN1MW (opsin 1 (cone pigments), medium-wave-sensitive). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CBBM; CBD; COD5; GCP; GOP; OPN1MW1

Description (Vector)

OPN1MW encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called green cone photopigment or medium-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. The long-wavelength opsin gene and multiple copies of the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of deutanopic colorblindness.

Gene ID

2652

Gene Name (Vector)

opsin 1 (cone pigments), medium-wave-sensitive

Gene Symbol

OPN1MW

HGNC ID

HGNC:4206

ORF Size (aa)

1095

ORF Size (bp)

1095 bp

RefSeq ID

NM_000513

RefSeq Synonyms

NM_000513, BC171755, BC171754, BC156776, BC143790, BC140938,

Species

human

UniGene ID

Hs.247787

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.