human OFD1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human OFD1.
shAAV-217372
AAV-h-OFD1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human OFD1 (OFD1, centriole and centriolar satellite protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
71-7A; CXorf5; JBTS10; RP23; SGBS2
Description (Vector)
OFD1 is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. Alternatively spliced transcripts have been described for this gene but the biological validity of these transcripts has not been determined.
Gene ID
8481
Gene Name (Vector)
OFD1, centriole and centriolar satellite protein
Gene Symbol
OFD1
HGNC ID
HGNC:2567
ORF Size (aa)
2919
ORF Size (bp)
2919 bp
RefSeq ID
NM_003611
RefSeq Synonyms
NM_003611, NM_001330210, NM_001330209, BC096344,
Species
human
UniGene ID
Hs.6483
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.