human NXF3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NXF3.
shAAV-217283
AAV-h-NXF3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NXF3 (nuclear RNA export factor 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
NXF3 is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.
Gene ID
56000
Gene Name (Vector)
nuclear RNA export factor 3
Gene Symbol
NXF3
HGNC ID
HGNC:8073
ORF Size (aa)
1596
ORF Size (bp)
1596 bp
RefSeq ID
NM_022052
RefSeq Synonyms
NM_022052, BC031616,
Species
human
UniGene ID
Hs.60386
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.