human NUDC shRNA silencing AAV

Name 
AAV-h-NUDC-shRNA
Cat No 
shAAV-217184
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NUDC.

shAAV-217184
AAV-h-NUDC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NUDC (nuclear distribution C, dynein complex regulator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HNUDC; MNUDC; NPD011; nuclear distribution C homolog; nuclear distribution gene C homolog; nuclear distribution protein C homolog; nuclear migration protein nudC; nudC nuclear distribution protein
Description (eCommerce)
Nuclear distribution protein C homolog (NUDC) is a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis [taken from NCBI Entrez Gene (Gene ID: 10726)].
Description (Vector)
NUDC encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2.
Gene ID
10726
Gene Name (eCommerce)
nuclear distribution C, dynein complex regulator
Gene Name (Vector)
nuclear distribution C, dynein complex regulator
Gene Symbol
NUDC
HGNC ID
HGNC:8045
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
996
ORF Size (bp)
996 bp
Protein Name (eCommerce)
Nuclear migration protein nudC
RefSeq ID
NM_006600
RefSeq Synonyms
NM_006600, BC021139, BC015153, BC007280, BC006147, BC003132, BC002399,
Research Areas
Cell Cycle,Cell Division,Cytoskeleton,Golgi Apparatus,Neurobiology,Neurodevelopment,PLK1 Signaling,Signal Transduction
Research Areas (Faceted)
cell_biology,cell_cycle,developmental_biology,genetics,neurobiology,signal_transduction
Species
human
Target Sentence
Nuclear distribution protein C homolog (NUDC) is a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis [taken from NCBI Entrez Gene (Gene ID: 10726)].
UniGene ID
Hs.263812
UniProt ID (eCommerce)
Q9Y266

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.