human NTRK2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NTRK2.
shAAV-217166
AAV-h-NTRK2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NTRK2 (neurotrophic receptor tyrosine kinase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GP145-TrkB; trk-B; TRKB
Description (Vector)
NTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene.
Gene ID
4915
Gene Name (Vector)
neurotrophic receptor tyrosine kinase 2
Gene Symbol
NTRK2
HGNC ID
HGNC:8032
ORF Size (aa)
1434
ORF Size (bp)
1434 bp
RefSeq ID
NM_006180
RefSeq Synonyms
NM_006180, NM_001291937, NM_001018066, NM_001018065, NM_001018064, NM_001007097, BC031835,
Species
human
UniGene ID
Hs.494312
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.