human NPY1R shRNA silencing AAV

Name
AAV-h-NPY1R-shRNA

Cat No
shAAV-217018

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NPY1R.

shAAV-217018

AAV-h-NPY1R-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NPY1R (neuropeptide Y receptor Y1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NPY1-R; NPYR

Description (Vector)

Neuropeptide Y (NPY; MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic smooth muscle (Herzog et al., 1992 (PubMed 1321422)).(supplied by OMIM, Mar 2008)

Gene ID

4886

Gene Name (Vector)

neuropeptide Y receptor Y1

Gene Symbol

NPY1R

HGNC ID

HGNC:7956

ORF Size (aa)

1155

ORF Size (bp)

1155 bp

RefSeq ID

NM_000909

RefSeq Synonyms

NM_000909, BC071720, BC036657,

Species

human

UniGene ID

Hs.519057

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.