human NOP56 shRNA silencing AAV

Name 
AAV-h-NOP56-shRNA
Cat No 
shAAV-216896
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NOP56.

shAAV-216896
AAV-h-NOP56-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NOP56 (NOP56 ribonucleoprotein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
NOL5A; NOP56 ribonucleoprotein homolog; nucleolar protein 56; Nucleolar protein 5A; nucleolar protein 5A (56kDa with KKE/D repeat); SCA36
Description (eCommerce)
Nucleolar protein 56 (NOP56) is a core component of the box C/D snoRNP complex. The snoRNP core complex is made up of NOP58, NOP56, and fibrillin and is involved in ribosome biogenesis.
Description (Vector)
Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined.
Gene ID
10528
Gene Name (eCommerce)
NOP56 ribonucleoprotein
Gene Name (Vector)
NOP56 ribonucleoprotein
Gene Symbol
NOP56
HGNC ID
HGNC:15911
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1785
ORF Size (bp)
1785 bp
Protein Name (eCommerce)
Nucleolar protein 56
RefSeq ID
NM_006392
RefSeq Synonyms
NM_006392, BC104793, BC104791, BC004937,
Research Areas
Apoptosis,Neurobiology,Neurodegeneration,Protein Folding,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,neurobiology,genetics,transcription_translation
Species
human
Target Sentence
Nucleolar protein 56 (NOP56) is a core component of the box C/D snoRNP complex. The snoRNP core complex is made up of NOP58, NOP56, and fibrillin and is involved in ribosome biogenesis.
UniGene ID
Hs.376064
UniProt ID (eCommerce)
O00567

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.