human NOM1 shRNA silencing AAV

Name 
AAV-h-NOM1-shRNA
Cat No 
shAAV-216874
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NOM1.

shAAV-216874
AAV-h-NOM1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NOM1 (nucleolar protein with MIF4G domain 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C7orf3; nucleolar MIF4G domain-containing protein 1; PPP1R113; protein phosphatase 1, regulatory subunit 113; SGD1; SGD1 homolog
Description (eCommerce)
NOM1 plays a role in targeting PPP1CA to the nucleolus. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5C9Z4].
Description (Vector)
Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 (PubMed 15715967)).(supplied by OMIM, Mar 2008)
Gene ID
64434
Gene Name (eCommerce)
nucleolar protein with MIF4G domain 1
Gene Name (Vector)
nucleolar protein with MIF4G domain 1
Gene Symbol
NOM1
HGNC ID
HGNC:13244
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2583
ORF Size (bp)
2583 bp
Protein Name (eCommerce)
Nucleolar MIF4G domain-containing protein 1
RefSeq ID
NM_138400
RefSeq Synonyms
NM_138400, BC167821,
Research Areas
Kinase/Phosphatase,RNA Binding,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,signal_transduction,transcription_translation
Species
human
Target Sentence
NOM1 plays a role in targeting PPP1CA to the nucleolus. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5C9Z4].
UniGene ID
Hs.15825
UniProt ID (eCommerce)
Q5C9Z4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.