human NHP2L1 shRNA silencing AAV

Name 
AAV-h-NHP2L1-shRNA
Cat No 
shAAV-216697
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human SNU13.

shAAV-216697
AAV-h-NHP2L1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human SNU13 (SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
U4/U6.U5 tri-snRNP 15.5 kD RNA binding protein; 15.5K; FA1; FA-1; high mobility group-like nuclear protein 2 homolog 1; hSNU13; NHP2 non-histone chromosome protein 2-like 1; NHP2L1; NHP2-like protein 1; NHPX; non-histone chromosome protein 2-like 1; OTK27; SNRNP15-5; SNU13 homolog; SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5); SPAG12; sperm specific antigen 1; SSFA1; U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 tri-snRNP 15.5 kDa protein
Description (eCommerce)
NHP2 non-histone chromosome protein 2-like 1 (NHP2L1) was originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene [taken from NCBI Entrez Gene (Gene ID: 4809)].
Description (Vector)
Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the (U4/U6.U5) tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
4809
Gene Name (eCommerce)
small nuclear ribonucleoprotein 13
Gene Name (Vector)
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
Gene Symbol
SNU13
HGNC ID
HGNC:7819
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
387
Protein Name (eCommerce)
NHP2-like protein 1
RefSeq ID
NM_001003796
RefSeq Synonyms
NM_005008, NM_001003796, BC095439, BC019282, BC005358,
Research Areas
Spliceosome
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
NHP2 non-histone chromosome protein 2-like 1 (NHP2L1) was originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene [taken from NCBI Entrez Gene (Gene ID: 4809)].
UniGene ID
Hs.182255
UniProt ID (eCommerce)
P55769

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.