human NGDN shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NGDN.
shAAV-216670
AAV-h-NGDN-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NGDN (neuroguidin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
C14orf120; CANu1; centromere accumulated nuclear protein 1; EIF4E-binding protein; eukaryotic initiation factor 4E and CPEB binding protein; LCP5; lpd-2; neuroguidin; neuroguidin, EIF4E binding protein; NGD
Description (eCommerce)
NGDN is an EIF4E-binding protein that interacts with CPEB and functions as a translational regulatory protein during development of the vertebrate nervous system. [taken from NCBI Entrez Gene (Gene ID: 25983)].
Description (Vector)
Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 (PubMed 16705177)).(supplied by OMIM, Mar 2008)
Gene ID
25983
Gene Name (eCommerce)
neuroguidin
Gene Name (Vector)
neuroguidin
Gene Symbol
NGDN
HGNC ID
HGNC:20271
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
948
ORF Size (bp)
948 bp
Protein Name (eCommerce)
Neuroguidin
RefSeq ID
NM_001042635
RefSeq Synonyms
NM_015514, NM_001042635, BC030817,
Research Areas
Neurobiology,Translational Control
Research Areas (Faceted)
cell_biology,neurobiology,transcription_translation
Species
human
Target Sentence
NGDN is an EIF4E-binding protein that interacts with CPEB and functions as a translational regulatory protein during development of the vertebrate nervous system. [taken from NCBI Entrez Gene (Gene ID: 25983)].
UniGene ID
Hs.9043
UniProt ID (eCommerce)
Q8NEJ9
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.