human NEUROD1 shRNA silencing AAV

Name 
AAV-h-NEUROD1-shRNA
Cat No 
shAAV-216610
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NEUROD1.

shAAV-216610
AAV-h-NEUROD1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NEUROD1 (neuronal differentiation 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BETA2; BHF-1; bHLHa3; MODY6; NEUROD
Description (Vector)
NEUROD1 encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
Gene ID
4760
Gene Name (Vector)
neuronal differentiation 1
Gene Symbol
NEUROD1
HGNC ID
HGNC:7762
ORF Size (aa)
1071
ORF Size (bp)
1071 bp
RefSeq ID
NM_002500
RefSeq Synonyms
NM_002500, BC009046,
Species
human
UniGene ID
Hs.709709

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.