human NEIL1 shRNA silencing AAV

Cat. No: shAAV-216563

Availability: 6-8 weeks

Name: AAV-h-NEIL1-shRNA

This is an AAV expressing shRNA for silencing of Human NEIL1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NEIL1
Gene Name: nei like DNA glycosylase 1
Gene ID: 79661
Gene Synonyms: FPG1; hFPG1; NEI1
ORF Size: 1173 bp
RefSeq#: NM_024608
Gene Description: NEIL1 is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.512732
HGNC ID: HGNC:18448