human NEIL1 shRNA silencing AAV

Name 
AAV-h-NEIL1-shRNA
Cat No 
shAAV-216563
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NEIL1.

shAAV-216563
AAV-h-NEIL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NEIL1 (nei like DNA glycosylase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FPG1; hFPG1; NEI1
Description (Vector)
NEIL1 is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
79661
Gene Name (Vector)
nei like DNA glycosylase 1
Gene Symbol
NEIL1
HGNC ID
HGNC:18448
ORF Size (aa)
1173
ORF Size (bp)
1173 bp
RefSeq ID
NM_024608
RefSeq Synonyms
NM_024608, NM_001256552, BC010876,
Species
human
UniGene ID
Hs.512732

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.