human NDUFB11 shRNA silencing AAV

Name 
AAV-h-NDUFB11-shRNA
Cat No 
shAAV-216504
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NDUFB11.

shAAV-216504
AAV-h-NDUFB11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CI-ESSS; ESSS; LSDMCA3; Np15; NP17.3; P17.3
Description (Vector)
NDUFB11 is a component of mitochondrial complex I. Complex I catalyzes the first step in the electron transport chain, the transfer of 2 electrons from NADH to ubiquinone, coupled to the translocation of 4 protons across the membrane (Carroll et al., 2002 (PubMed 12381726)).(supplied by OMIM, Feb 2009)
Gene ID
54539
Gene Name (Vector)
NADH:ubiquinone oxidoreductase subunit B11
Gene Symbol
NDUFB11
HGNC ID
HGNC:20372
ORF Size (aa)
492
RefSeq ID
NM_019056
RefSeq Synonyms
NM_019056, NM_001135998, BC107805, BC010665,
Species
human
UniGene ID
Hs.521969

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.