human NDUFA13 shRNA silencing AAV

Name 
AAV-h-NDUFA13-shRNA
Cat No 
shAAV-216475
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NDUFA13.

shAAV-216475
AAV-h-NDUFA13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NDUFA13 (NADH:ubiquinone oxidoreductase subunit A13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
B16.6; CDA016; CGI-39; GRIM-19; GRIM19
Description (Vector)
NDUFA13 encodes a subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain. The protein is required for complex I assembly and electron transfer activity. The protein binds the signal transducers and activators of transcription 3 (STAT3) transcription factor, and can function as a tumor suppressor. The human protein purified from mitochondria migrates at approximately 16 kDa. Transcripts originating from an upstream promoter and capable of expressing a protein with a longer N-terminus have been found, but their biological validity has not been determined.
Gene ID
51079
Gene Name (Vector)
NADH:ubiquinone oxidoreductase subunit A13
Gene Symbol
NDUFA13
HGNC ID
HGNC:17194
ORF Size (aa)
435
RefSeq ID
NM_015965
RefSeq Synonyms
NM_015965, BC009189,
Species
human
UniGene ID
Hs.534453

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.