human NDUFA12 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NDUFA12.
shAAV-216474
AAV-h-NDUFA12-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
B17.2; DAP13
Description (Vector)
NDUFA12 encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.
Gene ID
55967
Gene Name (Vector)
NADH:ubiquinone oxidoreductase subunit A12
Gene Symbol
NDUFA12
HGNC ID
HGNC:23987
ORF Size (aa)
438
RefSeq ID
NM_018838
RefSeq Synonyms
NM_018838, NM_001258338, BC005936,
Species
human
UniGene ID
Hs.506374
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.