human NDST3 shRNA silencing AAV

Name 
AAV-h-NDST3-shRNA
Cat No 
shAAV-216467
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NDST3.

shAAV-216467
AAV-h-NDST3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NDST3 (N-deacetylase and N-sulfotransferase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HSST3
Description (Vector)
NDST3 encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin.
Gene ID
9348
Gene Name (Vector)
N-deacetylase and N-sulfotransferase 3
Gene Symbol
NDST3
HGNC ID
HGNC:7682
ORF Size (aa)
2622
ORF Size (bp)
2622 bp
RefSeq ID
NM_004784
RefSeq Synonyms
NM_004784, BC109310, BC109309,
Species
human
UniGene ID
Hs.480596

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.