human NDRG4 shRNA silencing AAV

Name
AAV-h-NDRG4-shRNA

Cat No
shAAV-216462

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human NDRG4.

shAAV-216462

AAV-h-NDRG4-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NDRG4 (NDRG family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BDM1; SMAP-8; SMAP8

Description (Vector)

NDRG4 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that is required for cell cycle progression and survival in primary astrocytes and may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Alternative splicing results in multiple transcripts encoding different isoforms.

Gene ID

65009

Gene Name (Vector)

NDRG family member 4

Gene Symbol

NDRG4

HGNC ID

HGNC:14466

ORF Size (aa)

1020

ORF Size (bp)

1020 bp

RefSeq ID

NM_020465

RefSeq Synonyms

NM_022910, NM_020465, NM_001242836, NM_001242835, NM_001242834, NM_001242833, NM_001130487, BC011795,

Species

human

UniGene ID

Hs.322430

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.