human NCR3 shRNA silencing AAV

Cat. No: shAAV-216433

Availability: 6-8 weeks

Name: AAV-h-NCR3-shRNA

This is an AAV expressing shRNA for silencing of Human NCR3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: NCR3
Gene Name: natural cytotoxicity triggering receptor 3
Gene ID: 259197
Gene Synonyms: 1C7; CD337; LY117; MALS; NKp30
ORF Size: 534 bp
RefSeq#: NM_147130
Gene Description: NCR3 is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.509513
HGNC ID: HGNC:19077