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human NAT8L shRNA silencing AAV

Name 
AAV-h-NAT8L-shRNA
Cat No 
shAAV-216351
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human NAT8L.

shAAV-216351
AAV-h-NAT8L-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human NAT8L (N-acetyltransferase 8 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CML3; NACED; NAT8-LIKE
Description (Vector)
NAT8L encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia).
Gene ID
339983
Gene Name (Vector)
N-acetyltransferase 8 like
Gene Symbol
NAT8L
HGNC ID
HGNC:26742
ORF Size (aa)
405
RefSeq ID
NM_178557
RefSeq Synonyms
NM_178557, BC103748, BC093908, BC093906,
Species
human
UniGene ID
Hs.318529

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.