human NAPRT1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human NAPRT.
shAAV-216318
AAV-h-NAPRT1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human NAPRT (nicotinate phosphoribosyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NAPRT1; PP3856
Description (Vector)
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).(supplied by OMIM, Mar 2008)
Gene ID
93100
Gene Name (Vector)
nicotinate phosphoribosyltransferase
Gene Symbol
NAPRT
HGNC ID
HGNC:30450
ORF Size (aa)
1545
ORF Size (bp)
1545 bp
RefSeq ID
NM_145201
RefSeq Synonyms
NM_145201, NM_001286829, BC032466, BC006284,
Species
human
UniGene ID
Hs.493164
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.