human MYST4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KAT6B.
shAAV-216252
AAV-h-MYST4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KAT6B (lysine acetyltransferase 6B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GTPTS; MORF; MOZ2; MYST4; qkf; querkopf; ZC2HC6B
Description (Vector)
KAT6B is a histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene.
Gene ID
23522
Gene Name (Vector)
lysine acetyltransferase 6B
Gene Symbol
KAT6B
HGNC ID
HGNC:17582
ORF Size (aa)
5346
ORF Size (bp)
5346 bp
RefSeq ID
NM_012330
RefSeq Synonyms
NM_012330, NM_001256469, NM_001256468, BC150618, BC150270,
Species
human
UniGene ID
Hs.599543
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.