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human MYO1C shRNA silencing AAV

Name 
AAV-h-MYO1C-shRNA
Cat No 
shAAV-216209
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MYO1C.

shAAV-216209
AAV-h-MYO1C-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MYO1C (myosin IC). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MMI-beta; MMIb; myr2; NMI
Description (Vector)
MYO1C encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.
Gene ID
4641
Gene Name (Vector)
myosin IC
Gene Symbol
MYO1C
HGNC ID
HGNC:7597
ORF Size (aa)
3087
ORF Size (bp)
3087 bp
RefSeq ID
NM_033375
RefSeq Synonyms
NM_033375, NM_001080950, NM_001080779, BC068013, BC044891,
Species
human
UniGene ID
Hs.286226

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.