human MYH8 shRNA silencing AAV

Name
AAV-h-MYH8-shRNA

Cat No
shAAV-216172

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MYH8.

shAAV-216172

AAV-h-MYH8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MYH8 (myosin heavy chain 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DA7; gtMHC-F; MyHC-peri; MyHC-pn

Description (Vector)

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome.

Gene ID

4626

Gene Name (Vector)

myosin heavy chain 8

Gene Symbol

MYH8

HGNC ID

HGNC:7578

ORF Size (aa)

5814

ORF Size (bp)

5814 bp

RefSeq ID

NM_002472

RefSeq Synonyms

NM_002472, BC172386,

Species

human

UniGene ID

Hs.700484

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.