human MYH6 shRNA silencing AAV

Name 
AAV-h-MYH6-shRNA
Cat No 
shAAV-216168
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MYH6.

shAAV-216168
AAV-h-MYH6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MYH6 (myosin heavy chain 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
alpha-MHC; ASD3; CMD1EE; CMH14; MYHC; MYHCA; SSS3
Description (Vector)
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located ~4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
Gene ID
4624
Gene Name (Vector)
myosin heavy chain 6
Gene Symbol
MYH6
HGNC ID
HGNC:7576
ORF Size (aa)
5820
ORF Size (bp)
5820 bp
RefSeq ID
NM_002471
RefSeq Synonyms
NM_002471, BC132667,
Species
human
UniGene ID
Hs.278432

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.