human MYH2 shRNA silencing AAV

Name
AAV-h-MYH2-shRNA

Cat No
shAAV-216164

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MYH2.

shAAV-216164

AAV-h-MYH2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MYH2 (myosin heavy chain 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IBM3; MYH2A; MYHas8; MyHC-2A; MyHC-IIa; MYHSA2; MYPOP

Description (Vector)

Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in inclusion body myopathy-3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene ID

4620

Gene Name (Vector)

myosin heavy chain 2

Gene Symbol

MYH2

HGNC ID

HGNC:7572

ORF Size (aa)

5826

ORF Size (bp)

5826 bp

RefSeq ID

NM_017534

RefSeq Synonyms

NM_017534, NM_001100112, BC126409,

Species

human

UniGene ID

Hs.699445

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.