human MXD4 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MXD4.
shAAV-216106
AAV-h-MXD4-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MXD4 (MAX dimerization protein 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHc12; MAD4; MST149; MSTP149
Description (Vector)
MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Gene ID
10608
Gene Name (Vector)
MAX dimerization protein 4
Gene Symbol
MXD4
HGNC ID
HGNC:13906
ORF Size (aa)
630
RefSeq ID
NM_006454
RefSeq Synonyms
NM_006454, BC068060, BC002713,
Species
human
UniGene ID
Hs.655020
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.