human MX2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MX2.
shAAV-216097
AAV-h-MX2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MX2 (MX dynamin like GTPase 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MXB
Description (Vector)
MX2 has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1.
Gene ID
4600
Gene Name (Vector)
MX dynamin like GTPase 2
Gene Symbol
MX2
HGNC ID
HGNC:7533
ORF Size (aa)
2148
ORF Size (bp)
2148 bp
RefSeq ID
NM_002463
RefSeq Synonyms
NM_002463, BC035293,
Species
human
UniGene ID
Hs.926
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.