human MTTP shRNA silencing AAV

Name
AAV-h-MTTP-shRNA

Cat No
shAAV-216056

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MTTP.

shAAV-216056

AAV-h-MTTP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MTTP (microsomal triglyceride transfer protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ABL; MTP

Description (Vector)

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

Gene ID

4547

Gene Name (Vector)

microsomal triglyceride transfer protein

Gene Symbol

MTTP

HGNC ID

HGNC:7467

ORF Size (aa)

2685

ORF Size (bp)

2685 bp

RefSeq ID

NM_000253

RefSeq Synonyms

NM_001300785, NM_000253, BC125111, BC125110,

Species

human

UniGene ID

Hs.195799

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.