human MSRB3 shRNA silencing AAV

Name
AAV-h-MSRB3-shRNA

Cat No
shAAV-215932

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MSRB3.

shAAV-215932

AAV-h-MSRB3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MSRB3 (methionine sulfoxide reductase B3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DFNB74

Description (Vector)

MSRB3 catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula.

Gene ID

253827

Gene Name (Vector)

methionine sulfoxide reductase B3

Gene Symbol

MSRB3

HGNC ID

HGNC:27375

ORF Size (aa)

558

RefSeq ID

NM_198080

RefSeq Synonyms

NM_198080, NM_001193461, NM_001193460, NM_001031679, BC040053,

Species

human

UniGene ID

Hs.339024

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.